Endocrine Abstracts

Background and aim: Pheochromocytoma, is a catecholamine-producing tumor, may rarely secrete other hormones such as adrenocorticotropic hormone (ACTH). We aimed to report a rare case of ectopic cushing syndrome due to malignant pheochromocytoma.Case report: A 42-year-old man admitted to outpatient clinic with headache, irritability, vomiting, nausea, and palpitation. He had paroxysmal hypertension and urinary fractionated metanephrines were measured appr...

Introduction and aims: It is known that obesity is associated with retinal microvascular changes. Optical coherence tomography (OCT), a new imaging technique, is used to visualize the choroid. In addition, OCT can also give more beneficial information about systemic and eye diseases. We aim to investigate whether or not obesity may impact on choroid and macula thickness.Material and methods: Forty-four subjects who were apply for obesity in our Endocrino...

Introduction and aim: Mean platelet volume (MPV) is a new important indicator of platelet activity in atherosclerosis. Elevated MPV is associated with the presence of more metabolically active platelets. The aim of our study is to evaluate whether change of MPV value is associated with cabergoline treatment in patients with prolactinoma.Materials and methods: Thirty patients with prolactinoma (mean age 33.4±8.5 years and body mass index (BMI): 28.1&...

Background and aim: Acromegaly is a rare endocrine disease and is associated with an increased prevalence of colorectal cancer and pre-malignant tubular adenomas, and also may be associated with other organ malignancies such as breast and thyroid. We report a rare case of acromegaly concomitant with adenocarcinoma arising from pancreas.Case report: A 52-year-old man who was diagnosed with acromegaly two years ago referred our outpatient clinic. After dia...

Background: Differential thyroid cancer (DTC) is classified into papillary, follicular and papillary micro thyroid cancer. Also, mean platelet volume (MPV) is an independent risk factor for cardiovascular disease. The aim of the present study was to investigate MPV values in DTC patients.Materials and methods: The levels of MPV were assessed in 183 patients with DTC 44 papillary thyroid cancer (mean age 43.±13.9) 34 papillary micro thyroid cancer (m...

Aim: Mean platelet volume (MPV), which is a determinant of platelet function, is an independent risk factor for atherosclerosis. The aim of this study is to evaluate MPV values in gestational diabetes mellitus (GDM).Material and methods: Forty-nine women with gestational diabetes mellitus (mean age 28.2±4.7 years) and 40 healthy pregnant women (mean 26.2±4.6 years age) who came to our Out-Patient Clinic of Endocrinology were included in the stu...

Introduction: Scleredema is a rare skin disease, clinically presents as diffuse, painless induration, and thickening of skin. It primarily affects the upper part of body and usually occurs in association with diabetes mellitus, infections or monoclonal gammopathy. We discussed a case of scleredema in patient with history of diabetes mellitus.Case report: A 54-year-old woman with history of long-standing, poorly-controlled diabetes mellitus, hypertension,...

Introduction and aim: The incidence of atherosclerotic vascular disease is high in obesity. Our aim is to determine the mean platelet volume (MPV) as a new indicator of atherosclerosis in morbid obesity.Materials and methods: Thirty-three patients with morbid obesity who applied to endocrinology department (mean age 41.5±11.3 years, body weight 118.2±16.9 kg and BMI: 45.9±7.2 kg/m2) and 39 age-matched (mean age 35.3±13.1 ye...

Introduction: The effects of sex steroids on lymphocytes count and functions are well known and it is propounded that autoimmune diseases more common in women. NLO index is an indicator of inflammative situation. In this study, it has been aimed that neutrophil/lymphocytes ratio (NLO) calculation by determining neutrophil/lymphocytes values in patients who diagnosed as hypogonadotropic hypogodanism and searching that whether there is significant difference between healthy grou...

Aim: Mean platelet volume (MPV) is considered a new indicator of atherosclerosis. Activated platelets and subclinical inflammation predispose to create for atherosclerotic heart disease. Larger platelets are metabolically more active than smaller ones and have more protrombotic potential. We have recently demonstrated that MPV levels in Hashimoto’s patients tend to be higher than healthy controls even if in euthyroid state. In present study we aimed to investigate a relat...